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Meet Dr. Torsak Tippairote
Asia’s First IFM Certified Practitioner
Physician-Scientist in Resilience Medicine | IFMCP | Toxicologist | Nutritionist | French Cuisine Chef
Dr. Torsak is a pioneer in metabolic resilience and personalized medicine. With more than three decades of experience in clinical care, research, and medical education, he has guided thousands of patients in uncovering the hidden bioenergetic cost of chronic stress adaptation and reclaiming their vitality.
He is the developer of the ERM framework—Exposure-Related Malnutrition—which explains how prolonged adaptation to lifestyle and environmental exposures gradually depletes the body’s metabolic reserves. This process of silent compromise—where energy is continually diverted from repair, regeneration, and long-term function—underlies many modern chronic conditions. His work brings together cutting-edge science and compassionate, systems-based care to address the deeper roots of erosion in health and resilience.
🧬 His Life’s Work — The ERM Framework
What Is ERM — Exposure-Related Malnutrition?
Exposure-Related Malnutrition (ERM) is a clinical and conceptual framework developed by Dr. Torsak to explain how prolonged stress, lifestyle, environmental toxin exposure, and chronic metabolic strain silently deplete the body’s adaptive capacity—often long before any diagnosable disease appears.
The ERM model helps clinicians and patients recognize early signs of functional decline, detect patterns of bioenergetic misallocation, and intervene before this silent erosion leads to chronic illness. This framework was peer-reviewed and published in Biogerontology—a Q1-ranked journal in the field of aging science—marking an important step toward advancing resilience-based approaches to health.
Get the study's full text at
Preprints.org
📖 His Book — From Adaptation to Exhaustion
“You’re not broken—you’re just exhausted.”
In this breakthrough guide, Dr. Torsak introduces the ERM framework to a wider audience—exploring why so many people feel drained, foggy, and dismissed by normal labs.
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🔬 Understand bioenergetic trade-offs
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🧩 Recognize early-stage fatigue
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🌿 Follow a personalized roadmap to recovery
Available now in English; Thai edition coming soon.
🎓 Academic Background & Interdisciplinary Training
Dr. Torsak’s academic journey spans medicine, nutrition science, toxicology, functional medicine, and even culinary arts—reflecting his deeply integrative and human-centered approach to healing.
🩺 Medical Doctor (MD)
Faculty of Medicine, Chiang Mai University, Thailand
His foundation in clinical medicine was shaped by one of Thailand’s most respected medical schools, where he first developed a systems-thinking approach to chronic disease.
🌿 Institute for Functional Medicine Certified Practitioner (IFMCP)
Institute for Functional Medicine, WA, USA
A certified IFM practitioner with a focus on root-cause, systems biology-based care for complex chronic illness.
☣️ Diet & Nutrition Toxicologist (MS)
Master of Science in Food and Nutrition Toxicology
Institute of Nutrition, Mahidol University, Thailand
Trained to understand how environmental and dietary exposures disrupt metabolic and immune function—core elements of the ERM model.
👨🍳 Diplôme de Cuisine – French Cuisine Chef
Le Cordon Bleu Dusit Culinary School, Bangkok, Thailand
Bringing culinary expertise into the therapeutic realm, he bridges nutritional biochemistry with real-world food-based healing.
🧬 Nutrition Scientist | PhD Candidate
Doctor of Philosophy in Nutrition
Faculty of Medicine Ramathibodi Hospital & Institute of Nutrition, Mahidol University
Currently pursuing doctoral research focused on nutritional resilience and the bioenergetic cost of stress adaptation.
🧠 Active Research & Ongoing Studies
🔬 Advancing the Science of Recovery
Dr. Torsak and his team are actively advancing the scientific foundation of Exposure-Related Malnutrition (ERM)—a model that links chronic stress, lifestyle, environmental exposures, and metabolic misallocation to the early erosion of health and resilience.
Their current research efforts focus on both evidence synthesis and real-world clinical validation, forming a bridge between conceptual science and patient-centered care.
🧪1. Systematic Review of ERM Biomarkers
Project Title: Bioenergetic Trade-Offs and Biomarker Signatures of Exposure-Related Malnutrition
PROSPERO ID: CRD420251033154
Objective:
To identify and map early-stage biomarkers associated with ERM, including markers of metabolic stress, neuroendocrine, immune modulation, redox imbalance, muscular system, cellular stress responses, and mitochondrial dysfunction. This review synthesizes data across human studies to develop a biomarker-driven staging model for ERM.
Status:
Literature screening complete; data extraction underway
Expected Output:
Peer-reviewed publication and open-access biomarker staging reference guide
📊 2. Retrospective Clinical Data Analysis
Project Title: Clinical Validation of ERM Staging and Recovery Outcomes
Objective:
To analyze over 1,000 patient records from functional and integrative care settings, identifying patterns of metabolic depletion, resilience loss, and response to lifestyle interventions across ERM stages.
Outcomes to be measured:
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Symptom patterns: fatigue, pain, cognitive function, exercise tolerance, pain score, symptom rating, quality of life score
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Functional markers: exercise performance, cognitive score, grip strength, balance, gait speed
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Biomarkers: acute phase reactants, housekeeping and intracellular proteins, long-term function proteins
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Recovery trajectories post-intervention (3–6 month windows)
Status:
Study protocol proposal phase; study tools and coding in progress
Expected Output:
Staging algorithm, case-based atlas, and clinical application guide
💚 Support the ERM Research Campaign
This work is made possible through a mix of institutional partnerships, personal funding, and community support. Research funding is actively being raised to accelerate:
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Data analysis and publication of findings
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Development of clinical tools (checklists, staging frameworks)
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Educational programs for clinicians and the public
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Thai-language dissemination and outreach
Your contribution directly supports this mission—to recognize depletion before disease and to restore health through science.
📚 Academic Research & Scientific Contributions
Scopus Author ID: 57193452745
ORCID: 0000-0003-3748-1920
Web of Science Researcher ID: AAG-5449-2021
Loop profile: 137557
Dr. Torsak has published over 25 peer-reviewed articles spanning nutrition, toxicology, metabolism, mitochondrial dysfunction, stress physiology, and environmental medicine.
Research articles
Exploring the Association Between Low-Level Mercury Exposure, Gut Barrier Dysfunction, and Parkinson’s Disease: A Case Series of Three Thai Patients.
Tippairote, T., Hoonkaew, P., Suksawang, A. et al. , SN Compr. Clin. Med. 7, 70 (2025). https://doi.org/10.1007/s42399-025-01829-z
The proteomics study of compounded HFE/TF/TfR2/HJV genetic variations in a Thai family with iron overload, chronic anemia, and motor neuron disorder.
Tippairote, T., Bjørklund, G., Peana, M. et al. J Mol Neurosci (2020). https://doi.org/10.1007/s12031-020-01676-8
Prevalence and Factors Associated with High Levels of Aluminum, Arsenic, Cadmium, Lead, and Mercury in Hair Samples of Well-Nourished Thai Children in Bangkok and Perimeters.
Tippairote T, Temviriyanukul P, Benjapong W, Trachootham D. Biological trace element research. 2018; doi:10.1007/s12011-018-1435-6
Hair Zinc and Severity of Symptoms Are Increased in Children with Attention Deficit and Hyperactivity Disorder: a Hair Multi-Element Profile Study.
Tippairote T, Temviriyanukul P, Benjapong W, Trachootham D. Biological trace element research. 2017;179(2):185-94. doi: 10.1007/s12011-017-0978-2
High iodine status in the hair samples of the well-nourished Thai Children
Tippairote, T., Yaovapak, A., Trachootham, D. J Food Sci Nutr. 2022; 8: 136. doi:10.24966/FSN-1076/100136
Review articles
From Adaptation to Exhaustion: Defining Exposure-Related Malnutrition as a Bioenergetic Phenotype of Aging.
Tippairote, T., Hoonkaew, P., Suksawang, A., & Tippairote, P. (2025). Preprints. https://doi.org/10.20944/preprints202504.1142.v3
Periodontitis Continuum: Antecedents, Triggers, Mediators, and Treatment Strategies
Asma Gasmi B., Tippairote T, Gasmi A, Noor S., Avdeev O., Bjørklund G. Current Medicinal Chemistry, 2024. 31: p. 1-25. DOI: 10.2174/0109298673265862231020051338
Early-Life Lead Exposure: Risks and Neurotoxic Consequences
Bjørklund G., Tippairote T. Hangan T., Chirumbolo S. Current Medicinal Chemistry, 2023. 30: p. 1-14. DOI: 10.2174/0929867330666230409135310
Traditional Chinese Medicine as the Preventive and Therapeutic Remedy for COVID-19
Gasmi A , Tippairote T. , Peana M. , Bjørklund G. Curr Med Chem, 2023. DOI: 10.2174/0929867330666230331084126
Metabolic Conditions and Peri-Implantitis.
Gasmi Benahmed, A.; Gasmi, A.; Tippairote, T.; Mujawdiya, P.K.; Avdeev, O.; Shanaida, Y.; Bjørklund, G. Antibiotics 2023, 12, 65. https://doi.org/10.3390/antibiotics12010
Combined Supplementation of Coenzyme Q10 and Other Nutrients in Specific Medical Conditions.
Tippairote, T.; Bjørklund, G.; Gasmi, A.; Semenova, Y.; Peana, M.; Chirumbolo, S.; Hangan, T. Nutrients 2022, 14, 4383. https://doi.org/10.3390/nu14204383
The continuum of disrupted metabolic tempo, mitochondrial substrate congestion, and metabolic gridlock toward the development of non-communicable diseases.
Tippairote, T., G. Bjørklund, and A. Yaovapak, Critical Reviews in Food Science and Nutrition, 2021. doi: 10.1080/10408398.2021.1907299
Micronutrients as immunomodulatory tools for COVID-19 management.
Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Geir Bjorklund. Clinical Immunology. 2020; 220:108545. doi: 10.1016/j.clim.2020.108545. Curr Med Chem, 2023.
Neurological Involvements of SARS-CoV2 Infection.
Gasmi, A., Tippairote, T., Mujawdiya, P.K. et al. Neurological Involvements of SARS-CoV2 Infection. Mol Neurobiol (2020). https://doi.org/10.1007/s12035-020-02070-6
Restoration of metabolic tempo through time-restricted eating (TRE) as the preventive measure for metabolic and neurodegenerative diseases
Tippairote, T., Janssen, S., Chunhabundit, R. 2020, Critical Reviews in Food Science and Nutrition. 2020:1-10. doi: 10.1080/10408398.2020.1781050
The roles of dietary, nutritional, and lifestyle interventions in adipose tissue adaptation and obesity.
Geir Bjørklund, Torsak Tippairote, Olga Borisova, Maryam Dadar, Fernando Lizcano, Jan Aaseth.
Current Medicinal Chemistry. 2020;27:1-19. doi: 10.2174/0929867327666200505090449
Individual risk management strategy and potential therapeutic options for the COVID-19 pandemic
Gasmi A, Noor S, Tippairote T, Menzel A, Bjørklund G.
Clinical Immunology. 2020; 108409. doi: 10.1016/j.clim.2020.108409
Developmental toxicity of arsenic: a drift from the classical dose–response relationship.
Bjørklund G, Tippairote T, Rahaman MS, et al.
Archives of Toxicology. 2020; 94:67–75. doi:10.1007/s00204-019-02628-x
Zinc Status in Hair Samples and Common Neurodevelopmental Disorders
Tippairote T, Trachootham D.
Journal of Neurology and Neuromedicine. 2017;2(10): 12-16. doi: 10.29245/2572.942X/2017/10.1158
Book chapter
Sources of Arsenic Exposure in Well-Nourished Children.
Tippairote T, Karnpanit W, Trachootham D.
Arsenic Water Resources Contamination: Challenges and Solutions. Fares A, Singh SK, editors. Springer International Publishing; 2019. p. 73-101. doi: 10.1007/978-3-030-21258-2_4
Conference Proceedings
A pilot case-control study of lead and other hazardous elements in hair samples and risk of attention deficit and hyperactivity disorders in Thai children.
Tippairote T, Temviriyanukul P, Benjapong W, Trachootham D.
Thai Journal of Toxicology. 2016; special issue: proceedings of the 7th National Conference in Toxicology (NCT7).
Short Communication
Individual risk management strategy for SARS-CoV2 infection: a step toward personalized healthcare
Tippairote, T., et al., International Immunopharmacology, 2021: p. 107629. doi: 10.1016/j.intimp.2021.107629
Oral presentation
Neuromodulation through Epidural Electrical Stimulation in Individuals with Spinal Cord Injury: A Glimpse of Light at the End of the Tunnel.
Tippairote T., Arj-aumnuyvipat P., Kunavongkrit K.
4th Annual Singapore Rehabilitation Conference 2015(SRC 2015). Tan Tock Seng Hospital & Singapore General Hospital.
Book
From Adaptation To Exhaustion: What If Fatigue, Weight Gain, and Brain Fog Aren’t Just in Your Head—But in Your Biology?
Tippairote, T. (2025). Healing Passion Press.
สมุทัยเวชศาสตร์: เปิดประตูสู่การรักษาการเจ็บป่วยเรื้อรังแนวใหม่ มุมมองของการรักษาการเจ็บป่วยเรื้อรัง โดยมุ่งที่เหตุแห่งทุกข์.
ทิพย์ไพโรจน์ ต. พิมพ์ครั้งที่ 2: กรุงเทพฯ; 2010: 192.