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A Personalized Management Offers a promising Approach to Alzheimer's Disease (AD) Treatment and Prevention

Alzheimer's Disease (AD) represents a complex network insufficiency that is influenced by various factors, including diet, lifestyle, stress, sleep, nutrient deficiencies, mental health, socialization, and toxins. Studies have shown that a single-drug approach may delay the progression of memory loss but, to date, has not prevented or reversed it. Therefore, a multi-therapeutic program, addressing multi-factorial optimization of network support and function, offers a more rational therapeutic strategy than a one-size-fits-all protocol.

A personalized program should address multiple factors simultaneously, including an individual's genetics, biochemistry, lifestyle, physical, and mental activity, as well as nutritional aspects. This individualized approach allows for the identification and attenuation of all the risk factors specific to each affected individual. A comprehensive approach to AD treatment and prevention could be more effective than traditional drug-based therapies in preventing or reversing cognitive decline.

Rao, R.V., et al., Rationale for a Multi-Factorial Approach for the Reversal of Cognitive Decline in Alzheimer’s Disease and MCI: A Review. International Journal of Molecular Sciences, 2023. 24(2): p. 1659.

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