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Efficacy of the Autoimmune Protocol Diet (AIP) as Part of Lifestyle Interventions

This study suggests that an online diet and lifestyle program facilitated by a multi-disciplinary team can significantly improve HRQLand symptom burden in middle-aged female subjects with HT. While there were no statistically significant changes noted in thyroid function or thyroid antibodies, the study’s findings suggest that AIP may decrease systemic inflammation and modulate the immune system as evidenced by a decrease in mean hs-CRP and changes in white blood cell (WBC) counts. Given the improvements were seen in the HRQL and participants’ symptom burden as well as markers of immune activity and inflammation, further studies in larger populations implementing AIP as part of a multi-disciplinary diet and lifestyle program are warranted.


Abbott RD, Sadowski A, Alt AG: Efficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimoto’s Thyroiditis. Cureus 2019, 11(4):e4556.