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How exposure to chronic stress contributes to the development of type 2 diabetes

Responses to stress are influenced by earlier experiences, sex, emotions, and cognition, and involve a complex network of neurotransmitters and hormones, which affect multiple biological systems. This study proposed a causal loop diagram (CLD) connecting these various mediators and processes relevant to T2D pathogenesis.


Merabet, N.; Lucassen, P.J.; Crielaard, L.; Stronks, K.; Quax, R.; Sloot, P.M.A.; la Fleur, S.E.; Nicolaou, M. How exposure to chronic stress contributes to the development of type 2 diabetes: A complexity science approach. Frontiers in neuroendocrinology 2022, 65, 100972, doi:https://doi.org/10.1016/j.yfrne.2021.100972.




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