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Inclusion of low carbohydrate diet for weight management showed benefits in RCT

This randomized clinical trial (RCT) of the inclusion of low-carbohydrate diet for intensive weight management into the general medical visit showed the lower diabetes medication use (mean difference in medication effect score, −0.5; 95%CI, −0.6 to −0.3; P < .001) and greater weight loss (mean difference, −3.7 kg; 95%CI, −5.5 to −1.9 kg; P < .001) at 48 weeks and approximately 50% fewer hypoglycemic events (incidence rate ratio, 0.49; 95%CI, 0.27 to 0.71; P < .001) during the 48-week period than did the general medical visit with medication management.

Estimated Trajectories by Arm for Diabetes Medication Effect From Hierarchical Linear Mixed Models

Yancy WS, Jr, Crowley MJ, Dar MS, Coffman CJ, Jeffreys AS, Maciejewski ML, Voils CI, Bradley AB, Edelman D: Comparison of Group Medical Visits Combined With Intensive Weight Management vs Group Medical Visits Alone for Glycemia in Patients With Type 2 Diabetes: A Noninferiority Randomized Clinical Trial. JAMA Internal Medicine 2019.

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