One hundred seventy-four patients with subjective cognitive decline and mild cognitive impairment were assigned individually tailored interventions including education/ pharmacologic/ nonpharmacologic for eighteen months. The results were shown by the improved cognition and reduced Alzheimer’s disease/cardiovascular risk scores
Isaacson RS, Hristov H, Saif N, Hackett K, Hendrix S, Melendez J, Safdieh J, Fink M, Thambisetty M, Sadek G, et al: Individualized clinical management of patients at risk for Alzheimer's dementia. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2019, 15(12):1588-1602.
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