Vitamin D deficit is associated with accelerated brain aging

Structural MRI data and vitamin D levels were obtained in 1,865 subjects from the general population.

Study results:

a.) There were associations between Vitamin D deficiency and increased brain aging.

b.) Vitamin D levels were positively associated with total brain and gray matter volumes.

c.) Hippocampal volumes showed no association with vitamin D levels.

Terock, J.; Bonk, S.; Frenzel, S.; Wittfeld, K.; Garvert, L.; Hosten, N.; Nauck, M.; Völzke, H.; Van der Auwera, S.; Grabe, H.J. Vitamin D deficit is associated with accelerated brain aging in the general population. Psychiatry Research: Neuroimaging 2022, 327, 111558, doi:https://doi.org/10.1016/j.pscychresns.2022.111558