Our mitochondria  are stress sensors . When they’re under pressure, the Integrated Stress Response (ISRmt)  kicks in to protect, repair,...

Proteins are the workhorses of life, performing nearly every cellular task. To function, they must fold into precise 3D shapes—a process...

Neuronal Senescence has a crucial impact on brain aging and neurodegenerative diseases. Senescent Cells have stopped dividing and show...

These tiny powerhouses generate ATP through oxidative phosphorylation, maintain calcium balance via the mitochondrial calcium uniporter,...

As we age, our immune system changes, leading to the accumulation of senescent T-cells. These cells can cause chronic inflammation, known...