Cardiovascular Health in T1D Patients on a 10-Year Ketogenic Diet

Adults with Type 1 Diabetes (T1D) are at a higher risk for cardiovascular disease (CVD) compared to the general population. A case report on T1D patients following a 10-year Ketogenic Diet (KD) found that a KD with ≤50g carbs/day can significantly improve glycemia, reduce HbA1c, and lower insulin load. Researchers compared 10-year KD data with normative T1D values and discovered that the diet helped achieve euglycemia (HbA1c 5.5%) and required lower insulin levels. Most importantly, it resulted in a below-average CVD risk. Significant metrics included a mean glucose level of 98mg/dL, seated systolic blood pressure (SBP) of 113mmHg, triglycerides at 69mg/dL, LDL at 129mg/dL, and a heart rate of 56bpm.

Further findings revealed a pulse wave velocity of 7.17m/s, flow-mediated dilation of 12.8%, and baroreflex gain of 23.5ms/mmHg, with no left ventricular diastolic dysfunction observed. These results suggest that, despite traditional concerns, a long-term Ketogenic Diet may offer substantial cardiovascular benefits for T1D patients. This groundbreaking research highlights the potential for dietary interventions to improve health outcomes in individuals managing Type 1 Diabetes.

Watso, J.C., et al., Advanced Cardiovascular Physiology in an Individual with Type 1 Diabetes After 10-Year Ketogenic Diet. American Journal of Physiology-Cell Physiology, 2024. 0(0): p. null.

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