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Epicardial Fat: The Overlooked Risk Factor for Heart Disease
When we think about visceral fat , abdominal fat gets most of the attention—it’s the deep fat around organs that drives insulin...
Jan 102 min read


The Next Frontier in Immunology: Organelle Immunity and Its Molecular Mechanisms
From antibodies in humoral immunity to T-cells in cellular immunity and barrier defenses in mucosal immunity , we’re now entering...
Jan 92 min read


Prevent, Manage, Reverse: The New Face of Chronic Disease Care
Chronic diseases like diabetes, heart disease, and stroke are responsible for 90% of healthcare costs and 74% of deaths worldwide. But...
Jan 81 min read


PCAge and LinAge: Your Personalized Guide to Aging Well
Exciting breakthrough: Researchers have developed PCAge , a next-generation biological aging clock with incredible precision to predict...
Jan 71 min read


Whole-Person Care: Multidisciplinary Strategies for Chronic Illness
Managing chronic health conditions like Type 2 Diabetes (T2D) requires more than just prescriptions—it takes a multidisciplinary team...
Jan 61 min read


The Hidden Balancers: How Insulin and Apelin Keep Your Metabolism in Check
Our body relies on Insulin and Apelin to manage blood sugar and fat metabolism, but what you eat—and when—can throw this balance off....
Jan 51 min read


Thyroid and Bioenergetics: Finding the Sweet Spot in Aging
As we age, our energy systems— bioenergetics —become less efficient, and thyroid hormones play a key role in keeping things running...
Dec 28, 20241 min read


Why Energy Runs Out: The Metabolic Mysteries of ME/CFS
Living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) can feel like trying to run a marathon without any fuel. Your...
Dec 27, 20242 min read


The Web of Life: How Inter-Organ Communication Shapes Aging and Metabolic Health
The latest review by Tokizane & Imai in Trends in Endocrinology & Metabolism unveils the central role of the hypothalamus as a control...
Dec 26, 20241 min read


Microbe- and Inflammation-Restricting (MIMs) Mechanisms: A New Lens on Early Immunity
🔬 Researchers have unveiled a novel framework for early antiviral defense: Microbe- and Inflammation-Restricting Mechanisms (MIMs) ....
Dec 25, 20241 min read


Not All Muscle Loss Is the Same: The Molecular Science Behind Sarcopenia and More
When it comes to muscle health, precision matters . Differentiating between sarcopenia , malnutrition , and cachexia is critical, as...
Dec 24, 20241 min read


Thermodynamics vs. Cellular Machinery: The Debate on Protein Folding
Proteins are the workhorses of life, performing nearly every cellular task. To function, they must fold into precise 3D shapes—a process...
Dec 23, 20242 min read


Are We Getting Enough Health for the Money Spent?
A study analyzed drugs approved by the National Institute for Health and Care Excellence (NICE) in England (2000–2020) and found a...
Dec 22, 20241 min read


Redefining PCOS: A Metabolic Perspective on a Complex Disorder
Polycystic Ovary Syndrome (PCOS) affects millions of women worldwide, and its roots lie in metabolic dysfunction . Here’s how two major...
Dec 20, 20241 min read


Unalamation & Counterregulation: The Key to Tackling Chronic Inflammation
Host with compromised nutrient network could trigger a cascade leading to chronic inflammation and disease🧬✨ Here’s how it works: 🛑 ...
Dec 19, 20241 min read


Why Fat Thresholds Matter: How East Asians Face High Metabolic Risk Without Obesity
In some populations, such as East Asians, individuals often develop type 2 diabetes and other non-communicable diseases (NCDs) despite...
Dec 18, 20242 min read


The Energy-Driven Landscape of Protein Folding: From Adaptation to Dysfunction
For decades, protein folding was seen as a spontaneous, thermodynamically driven process —where proteins naturally fall into their most...
Dec 17, 20241 min read


Rewriting Obesity Science: A Metabolic Perspective
What if we’ve been tackling obesity all wrong? 🤔 The traditional “calories in, calories out” model ( Energy Balance Model, EBM ) is...
Dec 16, 20241 min read


Tackling T2D Effectively: Is Weight Loss Enough?
While GLP-1 receptor agonists have revolutionized Type 2 Diabetes (T2D) care with their weight-loss benefits, are they truly addressing...
Dec 16, 20241 min read


Combatting MASLD: A 360° View of Causes, Risks, and Treatments
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global epidemic impacting 38% of the population 🌍. It’s...
Dec 14, 20241 min read
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