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The Hidden Balancers: How Insulin and Apelin Keep Your Metabolism in Check

Our body relies on Insulin and Apelin to manage blood sugar and fat metabolism, but what you eat—and when—can throw this balance off.


In the Fasted State:

  • Insulin: LOW. Your body burns fat for energy.

  • Apelin: HIGH. Supports fat burning, improves insulin sensitivity, and prevents blood sugar spikes.


In the Fed State (After Meals):

  • Insulin: SPIKES to store glucose and fat.

  • Apelin: TEMPORARILY RISES to help insulin move glucose into cells and promote fat metabolism.


When Carbs Overload:

  • Frequent high-carb meals lead to chronic high insulin, causing:

    • Reduced Apelin secretion.

    • Poor glucose uptake and fat burning.

    • Increased fat storage and insulin resistance.


How to Stay Balanced:

  • Choose complex carbs like veggies and whole grains.

  • Pair carbs with protein and fiber to avoid insulin spikes.

  • Space meals or try fasting to let Apelin do its job.

  • Stay active to boost insulin sensitivity.


Support your body’s natural balance—Apelin and Insulin are your allies when you work with them, not against them! 💪✨

Li, C., Cheng, H., Adhikari, B. K., Wang, S., Yang, N., Liu, W.,…Wang, Y. (2022). The Role of Apelin–APJ System in Diabetes and Obesity [Review]. Frontiers in Endocrinology, 13. https://doi.org/10.3389/fendo.2022.820002




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