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When the Skin Remembers: How Everyday Exposures Strengthen Our Defenses
A new review in eLife by Gres et al. (2025) , “Trained Immunity in Skin Infections: Macrophages and Beyond,” offers a fascinating...
Oct 11, 20253 min read


Why Hydration Shapes Your Stress Response — and Long-Term Health
A new study published in the Journal of Applied Physiology (Kashi et al., 2025) has uncovered something many of us overlook: how much...
Oct 3, 20252 min read


When T Cells Run Out of Fuel: How Stress, Metabolism, and Aging Shape Our Immune Defenses
A new review in Trends in Endocrinology & Metabolism (Shangguan et al., 2025) explores why our immune soldiers — CD8+ T cells — so...
Sep 30, 20253 min read


When Medications Borrow from Tomorrow: Glucocorticoids, Bone Health, and the Hidden Cost of Survival
A new review in The Lancet Diabetes & Endocrinology (Hofbauer et al., 2025) takes a deep dive into a problem that doctors have...
Sep 29, 20252 min read


When Stress Runs Out of Fuel: What Critical Illness Teaches Us About Hidden Trade-Offs
A 2022 paper in the Journal of Clinical Endocrinology & Metabolism (Téblick, Gunst, & Van den Berghe, 2022) revisits a long-debated...
Sep 20, 20253 min read


Stress Hyperglycemia Ratio: A Simple Biomarker with Big Implications for Exposure-Related Malnutrition (ERM)
A new study in BMC Infectious Diseases (Feng et al., 2025) has shed light on the prognostic value of the stress hyperglycemia ratio...
Sep 19, 20252 min read


When Healing Turns Costly: What Burn Injuries Teach Us About the Body’s Energy Trade-Offs
A recent review published in Acute Medicine & Surgery by Osuka and colleagues (2024) explored the systemic immune response to burn...
Sep 17, 20252 min read


When the Immune System Trains Too Hard
Trained Immunity, Immunometabolism, and the Energy Cost of Resilience A new review in the Journal of Clinical Investigation (Sviridov,...
Sep 14, 20253 min read


Sepsis as an Energy Crisis: Why the Immune System Fails Without Fuel
Sepsis remains one of medicine’s greatest challenges. Patients often arrive in intensive care with infections that spiral into two...
Sep 9, 20254 min read


🧠 When Good Intentions Backfire: What Happens When We Micromanage Cholesterol?
In the world of heart health, lowering cholesterol has long been seen as a clear win. Fewer heart attacks. Less plaque buildup. Better...
Sep 6, 20253 min read


When Sleep Debt Tips the Scales: Testosterone, Cortisol, and the Metabolic Cost of Resilience
Sleep is more than rest—it is a cornerstone of how our bodies balance energy, repair tissues, and adapt to the challenges of life. A...
Sep 5, 20253 min read


When the Immune System Loses Its Rhythm: Aging, Diversity, and the Energy Cost of Resilience
A new review in Nutrients (Yu et al., 2024) takes a deep dive into how our immune system changes with age — and why those changes leave...
Aug 13, 20253 min read


🌀 Bipolar, Bears, and Burnout: What Mood Disorders Can Teach Us About Metabolic Rhythms
What if bipolar disorder wasn’t just “in your head”—but also in your mitochondria, your metabolism, your light exposure, and your...
Aug 10, 20253 min read


🧠 Rethinking Brain Aging: Why Your Mind Might Be Smarter Than Evolution Thinks
We’ve long been told that aging is a slow, inevitable decline—our cells wear out, our systems falter, and we gradually lose the capacity...
Aug 6, 20253 min read


🔥 When the Fire Within Burns Too Long: How Mitochondria, Inflammation, and Stress Adaptation Are Connected
What if your immune system wasn’t just reacting to infections—but was also deeply shaped by how your body manages energy and stress over...
Aug 5, 20253 min read


Biomarker Signatures and the Future of Aging: Why Patterns Matter More Than Points
What if your lab results could tell the story of how you're aging—not just whether you're “normal”? In traditional medicine, we’re...
Aug 4, 20253 min read


Are You Training or Draining? How Muscle Stress, Recovery, and Adaptation Align with the ERM Framework
August 2025 In the world of sports science and functional medicine, we often talk about building strength, improving performance, and...
Aug 3, 20254 min read


💇♀️ Hair Loss and Hormones: A Deeper Look Beyond the Follicle
Hair loss is often dismissed as a cosmetic concern—something to cover up or treat with shampoos and pills. But in medicine, the surface...
Aug 2, 20253 min read


🧠 Resilience, Brain Health, and the Hidden Cost of Adaptation
How a New Global Framework Aligns with the ERM Model Resilience is often celebrated as an inner strength—a badge of honor for those who...
Aug 1, 20253 min read


🧬 Rethinking Diabetes: What the YODA Study Reveals About a Missing Diagnosis
July 2025 When we think of diabetes, we usually picture two types: Type 1 – an autoimmune attack on insulin-producing cells, mostly in...
Jul 25, 20254 min read
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