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Avoiding Ultra-Processed Foods May Be Key to Fighting Obesity
A randomized controlled trial (RCT) conducted by the NIH Clinical Center provides evidence for the impact of ultra-processed foods on...
Feb 26, 20241 min read


Autopsy Reveals Inflammatory Response to COVID-19 Vaccine in a Parkinson's Patient: Spike Protein Detected, Nucleocapsid Protein Absent
This case report presents the case of a 76-year-old male patient with Parkinson's disease who died three weeks after receiving his third...
Feb 25, 20241 min read


Are you one of the salt lovers?
A recent global study found that sodium intake may not shorten life span and may even be positively associated with healthy life...
Feb 25, 20241 min read


Aging Does Not Always Mean Poor Cognition
A study showed that poor cognition is not necessarily tied to age. Aging only accounted for 23% of cognitive decline in older Americans....
Feb 24, 20241 min read


1.7. The host nutrient reserve: a critical modulator of Integrated Stress Response.
The host nutrient reserve plays a critical role in the Integrated Stress Response (ISR). The reserve encompasses the presence of macro-...
Feb 24, 20241 min read


Episode 1.2 Hormesis
How exposomes shape diverse biological shields and determine host tolerance or vulnerability. Lethal exposure can have fatal...
Feb 14, 20242 min read


1.6. Mitochondria and Endoplasmic reticulum: The Yin and Yang of Catabolism and Anabolism
The metabolic balance between catabolism in the mitochondria and anabolism in the endoplasmic reticulum (ER) is essential for maintaining...
Feb 13, 20242 min read


Episode 1.1 Exposomics
Therapeutic Lifestyle Changes Video Series
Feb 13, 20241 min read


1.5. Integrated Stress Responses (ISR): The linchpin of chronic and age-related illnesses
The integrated stress response (ISR) is a complex biological response to a wide range of environmental and physiological challenges. In...
Feb 11, 20242 min read


1.4. Genome-Exposome Interactions: Unlocking the Chronic Illnesses Mysteries
Various Genome-Wide Association Studies (GWAS) have revealed a relationship between multiple genetic susceptibilities and chronic...
Feb 9, 20241 min read


1.3. Chronic illness processes start when the total exposome load exceeds the host tolerance
The risk of developing an acute disease rises when a threat, either a virus, bacteria, fungus, or environmental toxin, is exposed at high...
Feb 9, 20242 min read


More vaccines, More protection?
A preprint of a study of 51,011 employees from the Cleveland Clinic in the United States. This was a relatively young population, with a...
Feb 8, 20241 min read


1.2. Exposome enables adaptive hormesis responses and shapes diverse biological shields: a linchpin of host tolerance and vulnerability.
Lethal exposure can have fatal consequences. On the contrary, small-dose exposures to certain stimuli can exert beneficial effects on...
Feb 8, 20242 min read


Vitamin D protects against depression
Evidence from an umbrella meta-analysis on ten randomized controlled trials and meta-analyses of four cohort studies confirms the...
Feb 7, 20241 min read


1.1. Exposomics : exploring the health consequences of host-environment homeodynamic interactions
The exposome explores the biomarkers of all exposures in an individual and their relevance to human health. External exposomes may derive...
Feb 7, 20241 min read


Consider iron status when evaluating infants at risk of delayed motor development.
Reticulocyte hemoglobin of <28 pg and ferritin <51 μg/L were associated with suboptimal gross motor scores (< 10th percentile rank) in...
Feb 5, 20241 min read


Retaining high lean mass and reducing fat mass could protect you from frailty
Body mass index (BMI) may not be an optimal predictor of frailty. Greater adiposity (% Body Fat) among women and abdominal obesity (Waist...
Feb 5, 20241 min read


What is your diet?
Caloric restriction (CR) has been known for nearly a century to extend life span and delay age-associated pathology in laboratory...
Feb 3, 20241 min read


Nighttime eating?
Nighttime eating has been linked to various metabolic outcomes including hyperlipidemia, hypertriglyceridemia, hyperglycemia, weight...
Feb 3, 20241 min read


How exposure to chronic stress contributes to the development of type 2 diabetes
Responses to stress are influenced by earlier experiences, sex, emotions, and cognition, and involve a complex network of...
Feb 3, 20241 min read
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